With Greek Origins, Alexie Is A Girl’s Name Meaning “man’s Defender.” A Unique And More Feminine Take On Alexander, This Name Still Has Many Ties To Historic Ruler Alexander The Great. Including Sharing An Identical Meaning. Those Who Pick The Name Are Often Attracted To Its History And Its Ability To Cross Cultures With Ease. Alexie Is A Clever Alternative For Those Who Like The Name Alexander Or Alexandria But Want To Give It A Modern Twist.